منابع مشابه
Programmed Cell Senescence during Mammalian Embryonic Development
Cellular senescence disables proliferation in damaged cells, and it is relevant for cancer and aging. Here, we show that senescence occurs during mammalian embryonic development at multiple locations, including the mesonephros and the endolymphatic sac of the inner ear, which we have analyzed in detail. Mechanistically, senescence in both structures is strictly dependent on p21, but independent...
متن کاملGenes and quantitative genetic variation involved with senescence in cells, organs, and the whole plant
Senescence, the deterioration of morphological, physiological, and reproductive functions with age that ends with the death of the organism, was widely studied in plants. Genes were identified that are linked to the deterioration of cells, organs and the whole plant. It is, however, unclear whether those genes are the source of age dependent deterioration or get activated to regulate such deter...
متن کاملAdvances in Plant Senescence
Senescence is an integral component of a plant’s lifecycle, which refers to changes that take place as the plant matures. A general distinction between plant senescence and animal senescence is the events observed in the animal kingdom typically steer growth while plant senescence orchestrates a massive shutdown or coordinated cell death in response to various stimuli designed to facilitate sur...
متن کاملSenescence and programmed cell death: substance or semantics?
The terms senescence and programmed cell death (PCD) have led to some confusion. Senescence as visibly observed in, for example, leaf yellowing and petal wilting, has often been taken to be synonymous with the programmed death of the constituent cells. PCD also obviously refers to cells, which show a programme leading to their death. Some scientists noted that leaf yellowing, if it has not gone...
متن کاملProgrammed Cell Death in Plant-pathogen Interactions.
Plants cope with pathogen attacks by using mechanisms of resistance that rely both on preformed protective defenses and on inducible defenses. The latter are the most well studied, and progress is being made in determining which induced responses are responsible for limiting pathogen growth. Many plant-pathogen interactions are accompanied by plant cell death. Recent evidence suggests that this...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 1997
ISSN: 1350-9047,1476-5403
DOI: 10.1038/sj.cdd.4400308